THE STUDY OF VARIATIONS OF THE BIOCHEMICAL PARAMETERS AT THE TESTED ANIMALS BY USING RED DEER ANTLER AS GUIDED TISSULAR REGENERATING MATERIAL

Authors: Paul Prodan, Silvia Mârţu

Abstract:

Considering the red deer antler’s rich content in biological active substances (BMP2, BMP4, IgF1, IgF2 şi PDGF), this paper aims to analize the use of this material, after a preliminary physio-chemical processing in order to obtain a biomaterial for the guided tissular regeneration (TGR). For this study, pigswere used as tested subjects, taking into account that these animals present biological similarities to the human body. The variations of alkaline phosphatase were analised, as an indicator of osteogenesys, as well as the variations of Ca, P, Mg ions and the A/G ratio (albumine/globuline), concerning the dynamic of the possible immune reactions of biomaterial rejection.

Keywords:
  • BIOCHEMISTRY
  • BIOMATERIAL
  • GUIDED TISSULAR REGENERATION