CONSIDERATIONS CONCERNING THE RELATIONSHIP BETWEEN APOPTOSIS AND SENESCENCE IN CONTEXT OF PARODENTIUM OR EDENTATED PATIENTS WHO SUFFER FROM CENTRAL NERVOUS SYSTEM DISEASES

Authors: Dana Cristina Bodnar, Anca Silvia Dumitriu, C.M. Varlan, Mariana Brandusa Popa, Virginia Varlan, T. Vaideanu

Abstract:

The cellular apoptosis and senescence, generally
considered, are extremely complex processes that lead to a
reduction in the cell number present in a pluricellular
bodies implying several intra and extra cellular mechanisms
and events. Finally, these processes lead to a diminishing
and even to cessation of the functions of a tissue/organ
resulting in the respective tissue/organ death. These are
processes characterizing also the structural components of
the dento-maxillary system that suffers from senescence
phenomena according to the biological age of the patient
or in a precocious form, as a result of the general disease
this system is subject to.
In the present paper, based on some clinical and
paraclinical observations and on the data gathered from
studied specialty literature we tried to establish the possible
relationship between serious parodontosis diseases and
different types of precocious edentation with great
destruction of the bone substratum in a direct relationship
with age of the patients suffering from neuraxial diseases.
The research results allow us to note that the genetic
or ischemic apoptosis can be accentuated. In the same
direction there can be interpreted the modifications made
by the neural growth factors.

Keywords:
  • APOPTOSIS
  • EDENTATION
  • NEURAXIAL DISEASEs
  • PARODONTOSIS
  • SENESCENCE