The study aims at identifying the growth disorders in children and adolescents suffering from syndrome Turner (45X0) and Klinefelter (47XXY), for a correct establishment of the subsequent treatment strategies. To this aim, a group of children and adolescents formed of 18 girls (9.5-17.5 year-old) and 8 boys (14.5-18.5 year-old) was investigated.
Analysis of these subjects evidenced dimensional modifications of the basis of the skull, of the maxillary and mandible length. The absence of a chromsome X or its supranumerary presence influences especially the shape and size of the skull basis, of the mandible and of the intermaxillary relations. Chromosomial X aneuploidy determines dimensional modifications of the anterior and posterior facial height.
- Klinefelter syndrome.
- sexual chromosomes
- Turner syndrome