Remineralization may be defined as the process through which the calcium and phosphate ions from external sources are brought into contact with the tooth, so that their deposition on the demineralized crystals is promoted, a gain of minerals being thus obtained. In latest decades, new preventive/therapeutical options have been proposed in order to ”heal” the subsurface non-cavitary carious lesions, such as the sealing and proximal infiltration method, fluorization (by means of slow release devices), new methods of white-spot lesions’ remineralization, modification of the cariogenity of the bacterial biofilm (ozono-therapy and probiotics), or measures for increasing enamel’s resistance to demineralization (laser therapy). Alternative treatments to fluoride therapy are represented by: products containing calcium phosphate (systems of remineralization with crystalline calcium phosphate – dihydrated dicalcic phosphate, tricalcic phosphate, bioactive glasses; systems containing amorphous unstabilized calcium phosphate; systems containing stabilized calcium phosphate), the SensiStat technology (calcium carbonate carriers), trimetaphosphate ion (TMP), self-assembling peptides, the Pro-Argin technology, hydroxyapatite nanoparticles (nanotechnology), the Anticay and the Pronamel technologies.
Keywords:- incipient caries lesions
- nonfluoride agents.
- remineralization